David Pertuit

 

UBE Assistant Researcher

• Master 2 of chemistry

In the Laboratory of Pharmacognosy, I work in the field of phytochemistry: my missions consist mainly in the extraction (microwave, ultrasound), the separation and isolation of natural molecules by various chromatographic methods. The structural analysis of isolated molecules, mainly saponins, is carried out using 1D and 2D NMR, and mass spectrometry.

Saponins, chromatography, NMR, mass spectrometry

• David Pertuit, Christine Belloir, Younes Bouizi, Clément Delaude, Mpuza Kapundu, Marie-Aleth Lacaille-Dubois, Loïc Briand, Anne-Claire Mitaine-Offer. Millettia dubia de Wild. (Fabaceae): Structural analysis of the oleanane-type glycosides and stimulation of the sweet taste receptors TAS1 R2/TAS1 R3. Phytochemistry (2024) 226, 114204.
• David Pertuit, Marc Sautour, Tomofumi Miyamoto, Clémment Delaude, Mpuza Kapundu, Marie-Aleth Lacaille-Dubois, Anne-Claire Mitaine-Offer. Oleanolic acid glycosides from two species of Olax: Olax wildemanii and Olax subscorpioideae. Phytochemistry Letters (2024) 60, 14–18.
• Samir Hobloss, Antoine Bruguière, David Pertuit, Tomofumi Miyamoto, Chiaki Tanaka, Christine Belloir, Marie-Aleth Lacaille-Dubois, Loïc Briand, Anne-Claire Mitaine-Offer. Activation of a sweet taste receptor by oleanane-type glycosides from Wisteria sinensis. Molecules (2022), 27, 7866.
• David Pertuit, Anne-Claire Mitaine-Offer, Tomofumi Miyamoto, Chiaki Tanaka, Clément Delaude, Pierre-Simon Bellaye, Bertrand Collin, Marie-Aleth Lacaille-Dubois. Oleanane-type glycosides isolated from the trunk barks of the Central African tree Millettia laurentii. Fitoterapia (2022) 159, 105193.
• David Pertuit, Anne-Claire Mitaine-Offer, Tomofumi Miyamoto, Chiaki Tanaka, Christine Belloir, Loic Briand, Marie-Aleth Lacaille-Dubois. Triterpenoid saponins from the cultivar “Green Elf” of Pittosporum tenuifolium. Molecules (2021), 26, 6805.