Martine BERTHELOT-GROSJEAN

https://www.cnrs.fr/en

 martine.berthelot-grosjean@u-bourgogne.fr

 martine.berthelot-grosjean@cnrs.fr

 HAL

 ORCID

CNRS Biological Engineer

Master in Biological Sciences (MSc) - Plant Science and Technologies - Oenology

After a job in Bayer’s group, Martine Berthelot-Grosjean joined the University of Illinois at Chicago in 2004. As a research specialist, she worked on the SNARE synaptic protein complex of Caenorhabditis elegans, in Prof. Richmond's team. In 2007, she joined Prof. Martin to help her setting up her laboratory at the University of Lausanne, she there worked on proteins involved in cell division and polarity in Schizosaccharomyces pombe.

Her work in the USA and Switzerland have contributed to the publication of scientific articles in PLoS Biology, The Journal of Neuroscience, Nature or Cell, for example.

Since 2010, Martine has been a Biological Engineer at the CNRS. Her research focuses on the olfactory behavior of Drosophila melanogaster. In this context, she has identified 2 acidic odors that drastically modify reproductive behavior and act as a powerful insect repellents. This work, funded by SATT-Sayens, led to the Drosomous patent deposit and the transfer of the corresponding operating license to a fruit-crop biocontrol company. During this period, she has supervised an assistant engineer and a master's student.

Martine takes part in the team's research work, co-authoring several articles published in e. g. Nature Communications, PLoS Biol.

Martine is also a Prevention Assistant and co-leader of the CSGA communication group AniCom.

Montanari M, Manière G, Berthelot-Grosjean M, Dusabyinema Y, Gillet B, Grosjean Y, Kurz CL, Royet J(2024). Larval microbiota primes the Drosophila adult gustatory response. Nat Commun. 13;15(1):1341. doi: 10.1038/s41467-024-45532-4.

Cavey M, Charroux B, Travaillard S, Manière G, Berthelot-Grosjean M, Quitard S, Minervino C, Detailleur B, Grosjean Y, Prud'homme B (2023). Increased sugar valuation contributes to the evolutionary shift in egg-laying behavior of the fruit pest Drosophila suzukii. PLoS Biol. 11;21(12):e3002432. doi: 10.1371/journal.pbio.3002432. 

Berthelot-Grosjean M, Manière G and Grosjean Y (2019). Repellent composition and uses. PCT/EP2020/075386.

Galagovsky D, Depetris-Chauvin A, Manière G, Geillon F, Berthelot-Grosjean M, Noirot E, Alves G, Grosjean Y(2018). Sobremesa L-type Amino Acid Transporter Expressed in Glia Is Essential for Proper Timing of Development and Brain Growth. Cell Rep.18;24(12):3156-3166.e4. doi: 10.1016/j.celrep.2018.08.067.

Ziegler AB, Augustin H, Clark NL, Berthelot-Grosjean M, Simonnet MM, Steinert JR, Geillon F, Manière G, Featherstone DE, Grosjean Y (2016). The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology, and Influences Locomotor Activity in Drosophila Larvae. Sci Rep. 25;6:19692. doi: 10.1038/srep19692.

Simonnet MM, Berthelot-Grosjean M, Grosjean Y (2014). Testing Drosophila olfaction with a Y-maze assay. J Vis Exp. 12;(88):51241. doi: 10.3791/51241.

Hachet O, Berthelot-Grosjean M, Kokkoris K, Vincenzetti V, Moosbrugger J, Martin SG (2011). A phosphorylation cycle shapes gradients of the DYRK family kinase Pom1 at the plasma membrane. Cell, 24;145(7):1116-28. doi: 10.1016/j.cell.2011.05.014.

Martin SG, Berthelot-Grosjean M (2009). Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle. Nature, 11;459(7248):852-6. doi: 10.1038/nature08054.

Gracheva EO, Burdina AO, Holgado AM, Berthelot-Grosjean M, Ackley BD, Hadwiger G, Nonet ML, Weimer RM, Richmond JE (2006). Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans. PLoS Biol., 4(8):e261. doi: 10.1371/journal.pbio.0040261.

Gracheva EO, Burdina AO, Touroutine D, Berthelot-Grosjean M, Parekh H, Richmond JE (2007). Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapses. J. Neurosci. 27(38):10176-84. doi: 10.1523/JNEUROSCI.2339-07.2007.