Christelle Lemaitre Guillier (PhD)

CNRS, Researcher

• Research associate. Identification and membrane proteins quantitative analysis by mass spectrometry using isotopic labelling. LSMBO University of Strasbourg. France
• Research associate. Purification of membrane BtuB receptor (vitB12) and demonstration of ion channel activities of E. coli toxins. University of East Anglia, Norwich, UK
• Doctor in Biology (Biophysics). Purification and characterization of antibacterial pore-forming proteins from fish skin mucosa. University of Rouen, France

Christelle is a CNRS Research engineer since 2003. After 2 post-Docs she was recruited at the IMBC Institute of Strasbourg to settle and later to manage the proteomic plateform for 3 Institutes. In 2008, she joined the Dijon Inrae center, in the “Mycorhize” team and then, in the « Grapevine immunity » team in 2012 to study plants/microorganisms interactions using “omics” approaches. She particularly took in charge i) the plant volatile organic compounds (VOC) emitted in response to SDP and/or to biotic stresses research thematic and ii) « omics » data analysis. In 2024, she joined the PERSING team at the CSGA to study the physiological impacts of acids exposures on drosophila in plant crop protection contexts. In late 2025, she arrived in the GustaBrain team to work on the understanding of mechanisms and unravel neuronal actors involved in the aversive feeding and associated memory in drosophila, but also the role of microbiota that might influence the « gut-brain » signal transduction.

Inventor of PPROVOC project for SATT SAYENS licence: Plant protection by using VOCs. Co-inventor ALGINATE project SATT SAYENS licence: Use of alginates oligomers to improve plant protection against pathogens.

Behavior, biochemistry, omics

• Trouvelot S & Lemaitre-Guillier C, Vallet J, Jacquens L, Douillet A, Harir M, Larignon P, Roullier-Gall C, Schmitt-Kopplin P, Adrian M and Fontaine F (2023). Sodium arsenite-induced changes in the wood of esca-diseased grapevine at cytological and metabolomic levels. Front. Plant Sci. 14:1141700.doi: 10.3389/fpls.2023.1141700

• Fernandez O, Lemaître-Guillier C, Songy A, Robert-Siegwald G, Lebrun MH, Schmitt-Kopplin P, Larignon P, Adrian M and Fontaine F (2023). The combination of both heat and water stresses may worsen Botryosphaeria dieback symptoms in grapevine. Plants 12(4):753. DOI: 10.3390/plants12040753

• Lemaitre-Guillier C, Chartier A, Dufresne C, Douillet A, Cluzet S, Valls J, Aveline N, Daire X, Adrian M (2022). Elicitor-induced VOC emission by grapevine leaves: characterisation in the vineyard. Molecules, 27(18), 6028; https://doi.org/10.3390/molecules27186028

• Lemaitre-Guillier C, Dufresne C, Chartier A, Cluzet S, Valls J, Jacquens L, Douillet A, Aveline N, Adrian M, Daire X (2021). VOCs are relevant biomarkers of elicitor-induced defences in grapevine. Molecules. 26:14. 4258 (18p.).

• Lemaitre-Guillier C, Fontaine F, Roullier-Gall C, Harir M, Magnin-Robert M, Clément C, Trouvelot S, Gougeon RD, Schmitt-Kopplin P, Adrian M (2020). Cultivar- and wood Area-dependent metabolomic fingerprints of grapevine infected by Botryosphaeria dieback. Phytopathology. Nov;110(11):1821-1837.

• Lemaître-Guillier C, Hovasse A, Schaeffer-Reiss C, Recorbet G, Poinssot B, Trouvelot S, Daire X, Adrian M, Héloir MC (2017). Proteomics towards the understanding of elicitor induced resistance of grapevine against downy mildew. J. Proteomics. 156:113.

• Guillier C, Cacas JL, Recorbet G, Deprêtre N, Mounier A, Mongrand S, Simon-Plas F, Wipf D, Dumas-Gaudot E (2014). Direct purification of detergent-insoluble membranes from Medicago truncatula root microsomes: comparison between floatation and sedimentation. BMC Plant Biol. Sep 30;14:255.

• Siroy A, Cosette P, Seyer D, Lemaître-Guillier C, Vallenet D, Van Dorsselaer A, Boyer-Mariotte S, Jouenne T, Dé E (2006). Global comparison of the membrane subproteomes between a multidrug-resistant Acinetobacter baumannii strain and a reference strain. J Proteome Res. Dec;5(12):3385-98.

• Mosbahi K & Lemaître C, Keeble AH, Mobasheri H, Morel B, James R, Moore GR, Lea EJ, Kleanthous C (2002). The cytotoxic domain of colicin E9 is a channel-forming endonuclease. Nat. Struct. Biol. Jun;9(6):476-84.

• Lemaître C, Orange N, Saglio P, Saint N, Gagnon J, Molle G (1996). Characterization and ion channel activities of novel antibacterial proteins from the skin mucosa of carp (Cyprinus carpio). Eur. J. Biochem. Aug 15;240(1):143-9.