Anne Vejux

 https://cv.hal.science/anne-vejux



Associate Professor, HDR - University of Burgundy

• Study of the cerebral inflammatory response toa high-fat diet in healthy subjects and patients with Parkinson's disease.
• Study of the cerebral inflammatory response toa high-fat diet in a mouse model: impact of oxysterols, oxidized cholesterolderivatives.

Teaching in biochemistry and molecular biology from L1 to M2.

• Elected member of the SAVAN department
• Head of Master 1 Management and Innovation in Biotechnologies (MIB) and Master 1 Assurance Qualité des Produits de Santé (AQPS).
• Member of the teaching committee for Master 2 Management and Innovation in Biotechnologies (MIB)

Neurodegenerative diseases, Brain, Inflammatory response, Lipids, Hypothalamus

• Yammine A, Ghzaiel I, Pires V, Zarrouk A, Kharoubi O, Greige-Gerges H, Auezova L, Lizard G, Vejux A. Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol - Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue. Curr Res Toxicol. 2024 Feb 8;6:100153. doi: 10.1016/j.crtox.2024.100153. PMID: 38379847; PMCID: PMC10877125.
  
  
• Schneider V, Vejux A, Nury T, Dupont G, Pais de Barros JP, Lakomy D, Lizard G, Moreau T. Neurodegeneration, oxidative stress and lipid metabolism plasma biomarkers to differentiate Parkinson's disease from atypical parkinsonian syndromes. Rev Neurol (Paris). 2023 Nov;179(9):961-966. doi: 10.1016/j.neurol.2022.12.015. Epub 2023 Jun 14. PMID: 37328356.
  
  
• Salvi J, Andreoletti P, Audinat E, Balland E, Ben Fradj S, Cherkaoui-Malki M, Heurtaux T, Liénard F, Nédélec E, Rovère C, Savary S, Véjux A, Trompier D, Benani A. Microgliosis: a double-edged sword in the control of food intake. FEBS J. 2024 Feb;291(4):615-631. doi: 10.1111/febs.16583. Epub 2022 Aug 2. PMID: 35880408.
  
  
• Ghosh S, Ghzaiel I, Vejux A, Meaney S, Nag S, Lizard G, Tripathi G, Naez F, Paul S. Impact of Oxysterols in Age-Related Disorders and Strategies to Alleviate Adverse Effects. Adv Exp Med Biol. 2024;1440:163-191. doi: 10.1007/978-3-031-43883-7_9. PMID: 38036880.
  
  
  
  
• Kessas K, Lounis W, Chouari Z, Vejux A, Lizard G, Kharoubi O. Benefits of rutin on mitochondrial function and inflammation in an aluminum-induced neurotoxicity rat model: Potential interest for the prevention of neurodegeneration. Biochimie. 2024 Feb 24;222:1-8. doi: 10.1016/j.biochi.2024.02.010. Epub ahead of print. PMID: 38408719.
  
  
  
  
• Ghzaiel I, Maaloul S, Ksila M, Namsi A, Yammine A, Debbabi M, Badreddine A, Meddeb W, Pires V, Nury T, Ménétrier F, Avoscan L, Zarrouk A, Baarine M, Masmoudi-Kouki O, Ghrairi T, Abdellaoui R, Nasser B, Hammami S, Hammami M, Samadi M, Vejux A, Lizard G. In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy. Adv Exp Med Biol. 2024;1440:437-452. doi: 10.1007/978-3-031-43883-7_21. PMID: 38036892.
  
  
  
  
• Zhor C, Wafaa L, Ghzaiel I, Kessas K, Zarrouk A, Ksila M, Ghrairi T, Latruffe N, Masmoudi-Kouki O, El Midaoui A, Vervandier-Fasseur D, Hammami M, Lizard G, Vejux A, Kharoubi O. Effects of polyphenols and their metabolites on age-related diseases. Biochem Pharmacol. 2023 Aug;214:115674. doi: 10.1016/j.bcp.2023.115674. Epub 2023 Jul 4. PMID: 37414102.
  
  
  
  
• Charrière K, Ghzaiel I, Lizard G, Vejux A. Involvement of Microglia in Neurodegenerative Diseases: Beneficial Effects of Docosahexahenoic Acid (DHA) Supplied by Food or Combined with Nanoparticles. Int J Mol Sci. 2021 Sep 30;22(19):10639. doi: 10.3390/ijms221910639. PMID: 34638979; PMCID: PMC8508587.
  
  
  
  
• Vejux A, Ghzaiel I, Nury T, Schneider V, Charrière K, Sghaier R, Zarrouk A, Leoni V, Moreau T, Lizard G. Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy. J Steroid Biochem Mol Biol. 2021 Jun;210:105870. doi: 10.1016/j.jsbmb.2021.105870. Epub 2021 Mar 5. PMID: 33684483.