Isabelle Chauvel

Scientist
Stéphane Fraichard

General information

ITA

TPI – Taste and Post-ingestive Integration

 Isabelle.chauvel@u-bourgogne.fr
 No Hal

Job

CNRS, Assistant Researcher

1985 : D.U.T applied biology IAB speciality, Dijon, France

Activities

Research theme
Isabelle began her career (17 years) in various private sector companies (pharmaceutical and food industries) as a laboratory technician, where she developed skills mainly in chemical analysis (liquid and gas chromatography). She then joined the CNRS in 2002 to work in Dijon on a brand new model: the drosophila. Since then, she has acquired considerable expertise in immunohistochemistry (immunofluorescence and in situ hybridization), microscopy (fluorescence microscope - Confocal Leica SP8 - Biphoton Nikon) and imaging: image capture (LAS X Leica software) and image processing (ImageJ, Fiji software). She shares her knowledge by training members of her team (researchers, engineers, technicians, PhD students, students) in immunohistochemistry, microscopy and imaging techniques. Over the years, she has also acquired expertise in molecular biology (RNA probe synthesis, cloning, PCR, qPCR), biochemistry (Western blots, electrophoresis, protein assays) and Drosophila behavior (courtship test, Proboscis Extension Response test ....). Isabelle is also deeply involved in safety issues in the workplace. It was only natural that she should become the Prevention Assistant for her team: she is responsible for ensuring that Health and Safety rules are respected within the team, and for training new recruits in good laboratory practice.
Scientific approach
Immunohistochemistry, In situ hybridization, Imaging, Microscopy, Molecular Biology, Prevention
Supervision
Isabelle supervised numerous students.
Key words
Taste, post-ingestion, neurosciences, Drosophila, behavior, metabolism, memory, imaging

Important publications

  • Fraichard S, Bouge AL, Chauvel I, Bouhin H (2006). Tenectin, a novel extracellular matrix protein expressed during Drosophila melanogaster embryonic development (2006) Gene Expr Patterns. Oct;6(8):772-6. doi: 10.1016/j.modgep.2006.01.007. Epub Feb 28. PMID: 16510317
  • Bousquet F, Houot B, Chauvel I, Dupas S, Ferveur JF (2009). desat1 and the evolution of pheromonal communication in Drosophila (2009) Ann N Y Acad Sci. Jul;1170:502-5. doi: 10.1111/j.1749-6632.2009.03927.x. PMID: 19686185
  • Fraichard S, Bougé AL, Kendall T, Chauvel I, Bouhin H, Bunch TA (2010). Tenectin is a novel alphaPS2betaPS integrin ligand required for wing morphogenesis and male genital looping in Drosophila. Dev Biol. Apr 15;340(2):504-17. doi: 10.1016/j.ydbio.2010.02.008. Epub 2010 Feb 10. PMID: 20152825
  • Bousquet F, Nojima T, Houot B, Chauvel I, Chaudy S, Dupas S, Yamamoto D, FerveurJF (2012). Expression of a desaturase gene, desat1, in neural and nonneural tissues separately affects perception and emission of sex pheromones in Drosophila. Proc Natl Acad Sci U S A. Jan 3;109(1):249-54. doi: 10.1073/pnas.1109166108. Epub 2011 Nov 23. PMID: 22114190
  • Bousquet F, Chauvel I, Flaven-Pouchon J, Farine JP, Ferveur JF (2016). Dietary rescue of altered metabolism gene reveals unexpected Drosophila mating cues. J Lipid Res. Mar;57(3):443-50. doi: 10.1194/jlr.M064683. Epub 2016 Jan 11. PMID: 26759364
  • Rihani K, Fraichard S, Chauvel I, Poirier N, Delompré T, Neiers F, Tanimura T, Ferveur JF, Briand L (2019). A conserved odorant binding protein is required for essential amino acid detection in Drosophila. Commun Biol. Nov 22;2:425. doi: 10.1038/s42003-019-0673-2. eCollection 2019. PMID: 31799428
  • Nojima T, Chauvel I, Houot B, Bousquet F, Farine JP, Everaerts C, Yamamoto D, FerveurJF (2019). The desaturase1 gene affects reproduction before, during and after copulation in Drosophila melanogaster. J Neurogenet. Mar-Jun;33(2):96-115. doi: 10.1080/01677063.2018.1559843. Epub 2019 Feb 6. PMID: 30724684
  • Fraichard S, Legendre A, Lucas P, Chauvel I, Faure P, Neiers F, Artur Y, Briand L, FerveurJF, Heydel JM (2020). Modulation of Sex Pheromone Discrimination by A UDP-Glycosyltransferase in Drosophila melanogaster. Genes (Basel). Feb 25;11(3):237. doi: 10.3390/genes11030237. PMID: 32106439

TPI – Taste and Post-ingestive Integration